Search Results - douglas+goetz

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[14001] Compositions that Modify Biological Signaling
The molecular mechanisms of normal physiology and pathology involve a network of biologically active molecules that interact via intertwined signaling processes. To unravel these complex mechanisms, reagents are needed that modify signaling processes. We describe here the compositions of organic compounds that modify biological signaling. Among a variety...
Published: 2/11/2020   |   Inventor(s): Stephen Bergmeier, Douglas Goetz, Mark McMills, Crina Orac, Frank Schwartz, Kelly McCall
Category(s): Life Science > Medical Diagnostics
Treatment of Non-Alcoholic Fatty Liver Disease [ID 14001, 14004, 14025]
OverviewNon-alcoholic fatty liver disease (NAFLD) is a disease of excess fat accumulation in the liver of individuals with no history of alcohol abuse which can lead to hepatitis, scarring, cirrhosis, and ultimately hepatic failure resulting in coma or death. It is the leading cause of liver transplantation and primary liver cancer in the U.S. The...
Published: 8/26/2019   |   Inventor(s): Kelly McCall, Frank Schwartz, Douglas Goetz, Ramiro Malgor
Category(s): Life Science > Therapeutics, Pharmaceuticals & Drug Delivery
Small Molecule for the Treatment of Equine Sepsis [ID 03007]
OverviewSepsis is a systemic inflammatory response to an infection and is responsible for nearly one-third of all foal mortality. Current treatment consists of broad-spectrum antibiotics, IV fluids, nutritional support, and administration of other medicines as the situation demands. Survival rates vary depending on the underlying cause of the disease...
Published: 10/23/2018   |   Inventor(s): Leonard Kohn, Douglas Goetz, Nilesh Harii, Nilesh Dagia, Cesidio Giuliani, Giorgio Napolitano
Category(s): Life Science > Medical Diagnostics