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[14001] Compositions that Modify Biological Signaling

The molecular mechanisms of normal physiology and pathology involve a network of biologically active molecules that interact via intertwined signaling processes. To unravel these complex mechanisms, reagents are needed that modify signaling processes. We describe here the compositions of organic compounds that modify biological signaling. Among a variety...

Published: 2/11/2020 | Inventor(s): Stephen Bergmeier, Douglas Goetz, Mark McMills, Crina Orac, Frank Schwartz, Kelly McCall

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Category(s): Life Science > Medical Diagnostics

Automated Computer Classifier of Diabetic Retinopathy [ID 15015]

OverviewWith an ever-increasing number of people being diagnosed with diabetes, it is imperative that new technologies be developed to effectively and efficiently monitor the disease and its associated comorbidities—including diabetic retinopathy, one of the leading causes of new blindness diagnoses in the U.S. Early diagnosis and targeted treatment...

Published: 11/4/2020 | Inventor(s): Mehmet Celenk, H. Bryan Riley, Frank Schwartz, Nikita Gurudath

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Category(s): Life Science > Medical Diagnostics

Treatment of Non-Alcoholic Fatty Liver Disease [ID 14001, 14004, 14025]

OverviewNon-alcoholic fatty liver disease (NAFLD) is a disease of excess fat accumulation in the liver of individuals with no history of alcohol abuse which can lead to hepatitis, scarring, cirrhosis, and ultimately hepatic failure resulting in coma or death. It is the leading cause of liver transplantation and primary liver cancer in the U.S. The...

Published: 8/26/2019 | Inventor(s): Kelly McCall, Frank Schwartz, Douglas Goetz, Ramiro Malgor

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Category(s): Life Science > Therapeutics, Pharmaceuticals & Drug Delivery